Extreme allergic reactions to COVID-19 vaccines are extraordinarily uncommon, CDC says

Out of the primary 1.9 million doses of Pfizer’s COVID-19 vaccine administered in america, there have been 21 reported circumstances of extreme allergic reactions to the vaccine, the Facilities for Illness Management and Prevention stated January 6.

The speed of anaphylaxis seen thus far — 11.1 circumstances per 1 million vaccine doses — is larger than for the flu vaccine, which is 1.three circumstances per 1 million doses, Nancy Messonnier, director of the CDC’s Nationwide Middle for Immunization and Respiratory Illnesses, stated in a Jan. 6 information briefing. However the reactions to COVID-19 vaccines are “nonetheless exceedingly uncommon,” she stated.

“These are secure and efficient vaccines. We’ve got good knowledge to point out that,” Messonnier stated. The nation’s surveillance programs for vaccine unwanted side effects are “extremely sturdy,” she stated, and “the one factor that we which have seen is these extreme allergic reactions.”

Nonetheless, websites that administer COVID-19 vaccines want to have the ability to acknowledge the indicators of anaphylaxis — which, if it happens, would almost certainly occur shortly after vaccination — and be ready to deal with it, CDC officers stated. And individuals who have a historical past of anaphylaxis in consequence any trigger ought to be noticed for 30 minutes after receiving a COVID-19 vaccine.

Anaphylaxis, which could be life-threatening, requires emergency therapy with epinephrine. The UK, which started immunizing its inhabitants in opposition to COVID-19 with the Pfizer vaccine December 8, was the primary nation to report circumstances of the extreme allergic response following vaccinations (SN: 12/11/20).

The CDC reported on the 21 circumstances in america, which cowl vaccinations given from December 14 to 23, in a Morbidity and Mortality Weekly Report examine printed on-line January 6. These first vaccinations have been solely with Pfizer’s vaccine. Officers don’t but know what’s inflicting the allergic response after immunization with the vaccine.

There have been no deaths from anaphylaxis reported within the examine. Nineteen of the 21 individuals have been handled with epinephrine and 4 have been hospitalized. Seven of the individuals within the report had skilled anaphylaxis up to now. CDC officers advocate that individuals with a historical past of anaphylaxis alert the particular person administering the shot earlier than getting it.

The CDC is constant to watch for these reactions. Because the report’s knowledge have been analyzed, the entire variety of reported reactions in america has grown barely to 29 circumstances. A few of these have been tied to vaccination with the Moderna COVID-19 vaccine, the company stated on the information briefing.

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